Magnesium Forms: Which to Choose. Magnesium is an essential dietary mineral found in generous amounts in green leafy vegetables such as spinach, nuts and seeds such as almonds and pumpkin seeds and several other foods. Having a sufficient intake from food sources and dietary supplements contributes to stronger bones, a healthy heart, good blood circulation, lowers high blood pressure, regulates heart rhythm and ensures an overall good muscle function and nerve health. But not all magnesium is the same. Some forms of the nutrient are actually better absorbed than others.
The amount of magnesium we absorb from one form or another dictates just how good the respective form of the mineral is for us. Naturally, we should go for the best forms, meaning those our body absorbs the most of. While we only take in 10 or 20% of most forms of magnesium, others may have an absorption rate of 50 or 60%, making them superior in quality and more likely to improve our health. So choosing the best form of magnesium in order to ensure the highest absorption rate possible is important if we want to enjoy all the health benefits of the mineral.
We take magnesium for muscle cramps (leg cramps and twitching, eyelid twitching), to increase the absorption of calcium in bones and help create new bone, help with palpitations, extrasystoles and other cardiovascular manifestations, relieve insomnia and sleep better, improve mood and so many other daily upsets. In reality, magnesium is much more important to us than treating minor manifestations. Research shows it is involved in over 350 chemical reactions within the human body and its presence is crucial for basic cellular processes.
Magnesium deficit has been shown to contribute to or accentuate conditions such as fibromyalgia, cardiovascular disease, osteoporosis, diabetes, depression and chronic fatigue syndrome. Intensive agricultural practices depleting our soil of essential nutrients that, in turn, leaves food less nutritious than it used to be, taking antacids, proton pump inhibitors and other stomach medicines that reduce stomach acidity and improve gastroesophageal reflux disease or gastritis, taking antidepressants or diuretics, suffering from malabsorption problems and other digestive conditions can all reduce our body’s magnesium reserves (for more information on how different medication and medical conditions can reduce our magnesium values, you can read the article The truth about magnesium).
Considering its wide range of action and involvement in so many aspects of our health, knowing which type of magnesium to take is crucial if we want to enjoy the health benefits it provides. So what makes a form of magnesium healthier than another? Its absorbance rate or how much of it our body successfully absorbs. However, there are other factors that weigh just as heavily:
1) The amounts our body can physically absorb (existing malabsorption problems reduce absorption).
2) Competitiveness of other nutrients (calcium, copper, iron, manganese, phosphorus maycompete with and reduce magnesium absorption).
3) Intake of nutrients that increase or facilitate magnesium absorption (vitamin D is believed to help increase absorption).
4) Dietary and lifestyle factors (alcohol and coffee consumption can deplete our magnesium reserves, soft drinks can impair it).
5) Cooking practices (soaking grains makes their nutrients more bioavailable, cooking certain foods reduces their oxalic acid content because oxalic acid reduces nutrient absorption in the gastrointesinal tract).
6) Unusually increased demands of the mineral, caused by stress or disease, paired with an insufficient intake.
Though there are various factors to consider when looking into increasing our magnesium intake and enjoying the health benefits it provides, choosing the right form also matters. This being said, here are the most and least helpful magnesium forms:
1) Magnesium oxide. This form is often prescribed for the treatment of duodenal and gastric ulcers, indigestion and gastroesophageal reflux due to its basic nature. It is also a strong laxative, hence its use for relieving constipation. However, taking too much can result in diarrhea and digestive upset. Magnesium oxide has a very poor gastrointestinal absorption rate, in certain individuals being significantly lower than 10% (usually 4%). Surprisingly, many multivitamin and multimineral complex supplements contain this very form of magnesium.
2) Magnesium sulfate. This particular form of magnesium is generally for intravenous use and for stopping preterm labor. It can be absorbed, to a certain extent, through the skin and is also the main ingredient in Epsom bath salts. These salts are added to bath water for the magnesium to be absorbed through the skin and help ease arthrits pain, muscle aches and stiff and swollen joints. It has a very low absorption rate.
3) Magnesium citrate. Magnesium citrate has a higher absorption rate than both magnesium oxide and magnesium sulfate and is suggested to be one of the best forms of the mineral in terms of bioavailability. From my experience, it is a great form of magnesium, quickly absorbed and with fast and visible effects. It is found in the famous Italian magnesium and potassium dietary supplement Polase. One aspect I’ve noticed when taking this type of magnesium is its effects are not as long-lasting compared to other forms with similarly high bioavailability.
4) Magnesium chloride. This particular form is actually better absorbed by the body than magnesium oxide and is not as strong a laxative as magnesium sulfate, but does loosen stools when taken in larger amounts. Because chloride is involved in the production of hydrochloric acid and thus influences digestion and nutrient absorption, it is believed to be a great option for people who do not produce sufficient stomach acid. Not having sufficient stomach acid means that we don’t digest food as we should, so we don’t absorb a maximum of nutrients from it either.
5) Magneziu carbonate. The consensus is that magnesium carbonate has one of the lowest absorption rate of all forms, thus being one of the cheapest and least helpful options when looking to prevent or correct a deficiency. It is estimated that it has an absorption rate of less than 10%, though some studies suggest its bioavailability may be as high as 20%. Overall, it is not the best form and exhibits laxative properties. However, it makes a great antacid.
6) Magnesium aspartate. With a high bioavailability, it is a great form of the mineral. Magnesium aspartate has been used together with potassium for improving and treating chronic fatigue syndrome. There have been warnings against the use of this particular form due to the fact that it is a synthetic product and may engender neurotoxicity, but even in such cases specific conditions have to be met. In my experience, magnesium aspartate is one of the best forms, with almost immediate results and long-lasting beneficial effects. For some time now I have been taking a Romanian brand called Aspacardin (it contains magnesium aspartate and potassium aspartate). From the first week I have noticed a significant improvement in sleep quality and mood.
Even in extremely stressful situations, I have managed to maintain my calm and a clear mind, I no longer get palpitations and extrasystoles and have a steady blood pressure. Also, because I’ve had severe problems with excess acidity and acid reflux and developed malabsorption issues due to prolonged use of antacids and proton pump inhibitors, I have found great relief in this supplement because it has helped me enjoy excellent energy levels, I no longer feel like fainting and enjoy better mood. Honestly, it has done wonders for me and, after taking it for about a year on and off, I have noticed I am feeling good even when I am off it.
7) Magnesium gluconate. Magnesium gluconate is believed to be a great choice for correcting magnesium deficiencies. In the right conditions, this form may have a higher bioavailability than citrate. Magnesium gluconate may cause diarrhea when taken in high doses. Also, the gluconic acid with which magnesium is paired is believed to contribute to higher energy levels due to its involvement in glucose (blood sugar) metabolism.
8) Magnesium glycinate. This form combines glycine, an amino acid and neurotransmitter with inhibitory action on the central nervous system with magnesium. This particular form has a sedative effect on the nervous system, induces relaxation and is known to help improve sleep quality and treat insomnia. It holds therapeutic effects for muscle aches and cramps and chronic fatigue syndrome. It lacks the laxative properties of other forms such as magnesium oxide. However, some people have reported magnesium glycinate may have stimulant effects in certain doses and may thus alter normal sleep patterns.
9) Magnesium malate. Preliminary studies suggest magnesium malate may prove useful in treating fibromyalgia pain. It generally has a good absorption rate, but it is not as efficient as magnesium citrate or aspartate. There have been reports of it causing loose stools and stomach upset. Magnesium malate may hold antimicrobial properties and increase saliva production.
10) Magnesium lactate. Magnesium lactate has a moderately good absorption rate and though it is superior to the oxide and sulfate forms and well tolerated, it is not the most efficient formula. This form is estimated to have a bioavailability of over 10%. Common side effects of taking large doses or prolonged use include digestive discomfort, bloating, flatulence and diarrhea.
11) Magnesium taurate. Taurine is found naturally in the bile and other parts of the digestive system of animals. Magnesium taurate is a magnesium salt of taurine. This particular form is suggested to contribute to improved muscle function, hence its cardiovascular benefits (improving the force of heart contractions) and induce relaxation due to taurine’s inhibitory effects on the nervous system.
12) Magnesium orotate. In addition to a good absorption rate, magnesium orotate contributes to increasing resistance to physical exercise and improving heart health, mainly because it is easily taken in the bloodstream. Just like magnesium taurate, it has a beneficial action when it comes to heart failure. However, animal research suggests that large doses of around 100 mg per kg per day may encourage tumour formation. This form is also more pricey than others, making it less desirable than citrate or aspartate, despite its relatively high bioavailability.
13) Magnesium pidolate (picolinate). Magnesium pidolate has a good absorption rate and is well tolerated by the human body. It is mainly recommended for treating hypomagnesemia (low levels of magnesium) and counteracting a potential deficiency. This form has also been investigated as a potential treatment for sickle cell anemia.
14) Magnesium-L-threonate. This particular type of magnesium has been shown to have a high absorption rate and good bioavailability. What makes it a good form is the fact that it can easily enter cells and tissues and cross the blood-brain barrier to exert its health effects, particularly support cognitive functions. Moreover, it does not have laxative properties. However, because of its low content of magnesium per dose, it might not be sufficient to correct deficiencies. Important. Magnesium stearate is not a dietary mineral, but a sort of additive.
Conclusion. When it comes to magnesium, absorption rates matter. We might be taking a 300 mg or 400 mg daily dose of magnesium to meet our demands, yet absorb less than 10% and still have a deficiency, despite taking supplements. Similarly, we might be taking a good form of magnesium and absorb most of it, enjoying a visible reduction of magnesium deficiency symptoms and an overall improved health. While other factors need to be taken into account as well, the form of magnesium we choose and its bioavailability and absorption rate do have a significant impact on our health.